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擅長(zhǎng)領(lǐng)域：研究領(lǐng)域?yàn)樯翅t(yī)學(xué)、圍產(chǎn)醫(yī)學(xué)和生殖遺傳學(xué)，主要研究方向?yàn)槿焉锩庖吣褪軝C(jī)制、生殖和妊娠相關(guān)疾病的免疫學(xué)病因與發(fā)病機(jī)制，以及遺傳性出生缺陷的防控研究。?

執(zhí)業(yè)經(jīng)歷： 1985年畢業(yè)于浙江醫(yī)科大學(xué)醫(yī)學(xué)系，2000-2001年在美國(guó)伊利諾依大學(xué)芝加哥分校(UIC)醫(yī)學(xué)院從事生殖生理學(xué)研究。研究領(lǐng)域?yàn)樯翅t(yī)學(xué)、圍產(chǎn)醫(yī)學(xué)和生殖遺傳學(xué)，主要研究方向?yàn)槿焉锩庖吣褪軝C(jī)制、生殖和妊娠相關(guān)疾病的免疫學(xué)病因與發(fā)病機(jī)制，以及遺傳性出生缺陷的防控研究。主持、承擔(dān)國(guó)家自然科學(xué)基金、973項(xiàng)目子課題等課題多項(xiàng)。發(fā)表學(xué)術(shù)論文百余篇，主要論文均發(fā)表在SCI刊物，獲國(guó)家科技進(jìn)步獎(jiǎng)二等獎(jiǎng)、浙江省科技進(jìn)步一等獎(jiǎng)等科技成果獎(jiǎng)勵(lì)6項(xiàng)。 　　研究方向： 　　生殖醫(yī)學(xué)、圍產(chǎn)醫(yī)學(xué) 　　主要在研課題： 　　1. Follistatin-like 3對(duì)滋養(yǎng)細(xì)胞與胚胎的影響以及在妊娠并發(fā)癥中的作用。2013年國(guó)家自然科學(xué)基金(課題負(fù)責(zé)人) 　　2. 子宮內(nèi)膜細(xì)胞脂肪酸結(jié)合蛋白4在胚胎著床中的作用與機(jī)制研究。2011年國(guó)家自然科學(xué)基金(課題負(fù)責(zé)人) 　　3. 輔助生殖誘發(fā)胚胎源性疾病的風(fēng)險(xiǎn)評(píng)估和機(jī)制研究。2011年國(guó)家重大科學(xué)研究計(jì)劃(973)項(xiàng)目(學(xué)術(shù)骨干) 　　4. Toll樣受體7、8介導(dǎo)的炎性反應(yīng)通路在滋養(yǎng)細(xì)胞阻止乙型肝炎病毒宮內(nèi)傳播中的作用。2010年浙江省自然科學(xué)基金(課題負(fù)責(zé)人) 　　近五年成果獲獎(jiǎng)： 　　1. 提高出生人口質(zhì)量的生殖技術(shù)創(chuàng)建、體系優(yōu)化與臨床推廣應(yīng)用：2010年國(guó)家科技進(jìn)步二等獎(jiǎng); 　　2. 阻斷出生缺陷、促進(jìn)子代健康關(guān)鍵技術(shù)體系的創(chuàng)建與推廣應(yīng)用：2010年浙江省科技進(jìn)步一等獎(jiǎng); 　　近五年發(fā)表的代表性論文(*為通訊作者)： 　　1. He J, Zhang AP, Fang M, Fang R, Ge JM, Jiang Y, Zhang H, Han C, Ye XQ, Yu DQ, Huang HF, Liu Y*, Dong MY*. Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies. BMC Genomics, 2013, 14:472. 　　2. Zhou QY, Li J, Wang HZ, Han C, Tian T, Zhu QY, Huang HF, Dong MY*. Serum preadipocyte factor-1 is increased in fetuses of pregnancy complicated with severe preeclampsia. Clinica Chimica Acta, 2013, 424:212-215. 　　3. Guo J, Tian T, Lu DH, Xia GY, Wang HZ, Dong MY*. Alterations of maternal serum and placental follistatin-like 3 and myostatin in pre-eclampsia. J Obstet Gynecol Res, 2012 Jul, 38( 7):988-996. 　　4. Hu DX, Tian T, Guo J, Wang HZ, Chen DQ, Dong MY*. Decreased maternal and placental concentrations of follistatin-like 3 in gestational diabetes. Clinica Chimica Acta, 2012, 413: 533-536. 　　5. Yin LJ, Zhang Y, Lv, PP, He WH, Wu YT, Liu AX, Ding GL, Dong MY, Qu F, Xu CM, Zhu XM, Huang HF. Insufficient maintenance DNA methylation is associated with abnormal embryonic development. BMC Med. 2012;10:26. 　　6. Liu FJ, Guo J, Tian T, Wang HZ, Dong FY, Huang HF, Dong MY*. Placental trophoblasts shifted Th1 ? Th2 balance toward Th2 and inhibited Th17 immunity at fetomaternal interface. APMIS, 2011, 119: 597–604. 　　7. Wang N, Wang, LY, Le F, Zhan QT, Zheng YM, Ding GL, Chen XJ, Sheng JZ, Dong MY, Huang HF, Jin F. Altered expression of Armet and Mrlp51 in the oocyte, preimplantation embryo, and brain of mice following oocyte in vitro maturation but postnatal brain development and cognitive function are normal. Reproduction, 2011,142( 3):401-408. 　　8. Chen D, Xia G, Xu P, Dong MY*. Peripartum serum leptin and soluble leptin receptor levels in women with gestational diabetes. Acta Obstet Gynecol Scand. 2010, 89(12): 1595- 1599. 　　9. Zhang K, He J, Dong MY*. Relationship between umbilical artery Doppler waveform analysis and perinatal prognosis in women with intrahepatic cholestasis of pregnancy. Int J Gynaecol Obstet. 2010;111(2):187-8. 　　10. Wang TT, Wu YT, Dong MY, Sheng JZ Leung PC, Huang HF. G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve. FERTILITY AND STERILITY. 2010; 94(6): 2490-2492. 　　11. Liang ZX, Dong MY, Cheng Q, Chen DQ. Gestational diabetes mellitus screening based on the gene chip technique. Diabetes Res Clin Pract, 2010 Aug, 89(2):167-73. 　　12. Qu F, Wang FF, Lu XE, Dong MY, Sheng JZ, Lv PP, Ding GL, Shi BW, Zhang D, Huang HF. Altered aquaporin expression in women with polycystic ovary syndrome: hyperandrogenism in follicular fluid inhibits aquaporin-9 in granulosa cells through the phosphatidylinositol 3-kinase pathway. HUMAN REPRODUCTION, JUN 2010, 25(6): 1441-1450 　　13. Ding GL, Chen XJ, Luo Q, Dong MY, Wang N, Huang HF. Attenuated oocyte fertilization and embryo development associated with altered growth factor/signal transduction induced by endometriotic peritoneal fluid. FERTILITY AND STERILITY, MAY 2010, 93(8): 2538-2544 　　14. Wei J, Wang HM, Yang XF, Dong MY, Wang ZP. Altered gene profile of placenta from women with intrahepatic cholestasis of pregnancy. Arch Gynecol Obstet, 2010 May, 281( 5): 801-10 　　15. Lou H, Ding W, Dong MY, Zhu Y, Zhou C, Wang Z, Yang X, Yao Q, Li D, Miao M. The Presence of Hepatitis B Surface Antigen in the Ova of Pregnant Women and Its Relationship with Intra-uterine Infection by Hepatitis B Virus. J Int Med Res, 2010, 38(1): 214-9 　　16. Tang L, Zhang Y, Pan H, Luo Q, Zhu XM, Dong MY, Leung PCK, Sheng JZ, Huang HF. Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell. Reprod Biol Endocrinol, 2009, 7: 　　17. Shangguan XJ, Liu FJ, Wang HZ, He J, Dong MY*. Alterations in serum adipocyte fatty acid binding protein and retinol binding protein-4 in normal pregnancy and preeclampsia. Clinica Chimica Acta, 2009, 407: 58-61 　　18. Chen DQ, Wang HZ, Huang HF, Dong MY*. Vascular Endothelial Growth Factor Attenuates Nω-Nitro-L-Arginine Methyl Ester-Induced Preeclampsia-Like Manifestations in Rats. Clinical and Experimental Hypertension. 2008 Oct, 30(7): 606- 615. 　　19. Chen X, Qian X, Chen H, Dong M*. Serum levels of nitric oxide metabolites during labour with or without combined spinal-epidural analgesia. EUROPEAN JOURNAL OF ANAESTHESIOLOGY. 2008 Sep, 25 (9): 708-713 　　20. Feng C, Wang LQ, Dong M, Huang HF. Need for standardization and confirmation of STS deletions on the Y chromosome – Reply. FERTILITY AND STERILITY. 2008 Aug, 90 (2): 464-464 　　21. Feng C, Wang LQ, Dong M*, Huang HF. Assisted reproductive technology may increase clinical mutation detection in male offspring. FERTILITY AND STERILITY, 2008 Jul, 90(1): 92-96. 　　22. Huang H, Dong M*. The effect of trohphoblasts on T lymphocytes and the role of indoamine 2,3-dioxigenase. Human Reproduction. 2007 Jul, 22 (Supl 1): 112-112 Meeting abstract O028. 　　23. Minyue Dong*, Guolian Ding, Jun Zhou, Hanzhi Wang,Yi Zhao, Hefeng Huang. The effect of trohphoblasts on T lymphocytes: Possible regulatory effector molecules--A proteomic analysis. Cellular Physiology and Biochemistry, 2008, 21:463-472. 　　24. Wensheng HU, Zhengping WANG，Hanzhi WANG, Hefeng HUANG and Minyue DONG*. Serum Visfatin Levels in Late Pregnancy and Preeclampsia. Acta Obstet Gynecol Scand, 2008 April, 87(4): 413-418. 　　25. Dongxiao Hu, Zhengping Wang, Wuwen Zhang, Hanzhi Wang, and Minyue Dong*. Alteration of Peripheral CD4+CD25+ Regulatory T Lymphocytes in Pregnancy and Preeclampsia. Acta Obstet Gynecol Scand, 2008, 87(2): 190-194. 　　26. Qingxia Meng, Huijuan Gao, Chengming Xu, Minyue Dong, Xia Sheng, Jiangzhong Sheng, Hefeng Huang. Reduced Expression and Function of Aquaporin-3 in Mouse Metaphase II Oocytes Induced by Controlled Ovarian Hyperstimulation Were Associated with Subsequent Low fertility Rate. Cell Physiol and Biochem, 2008; 21: 123-128. 詳細(xì)介紹