朱志華
中山大學(xué)附屬腫瘤醫(yī)院胸外科
擅長(zhǎng)領(lǐng)域:肺癌外科胸腔鏡微創(chuàng)手術(shù)及綜合治療?
執(zhí)業(yè)經(jīng)歷: 中山大學(xué)腫瘤防治中心胸科副教授、副研究員、碩士研究生導(dǎo)師。擅長(zhǎng)肺癌的微創(chuàng)外科治療、復(fù)雜手術(shù)治療和個(gè)體化綜合精準(zhǔn)治療。2010年獲廣東省丁穎科技獎(jiǎng),2015年獲廣東省科技進(jìn)步獎(jiǎng)一等獎(jiǎng)。在專(zhuān)業(yè)醫(yī)學(xué)期刊Lancet(IF 40)、JCO(IF 18)、JTD、APM等發(fā)表SCI論文30余篇。2012年共同發(fā)起并和團(tuán)隊(duì)一起創(chuàng)立了專(zhuān)業(yè)醫(yī)學(xué)期刊Annals of Palliative Medicine(2015年被Pubmed/Medline收錄),目前擔(dān)任主編之一,這是亞太地區(qū)第一本關(guān)注姑息醫(yī)學(xué)領(lǐng)域的全英文期刊。 教育背景和工作經(jīng)歷 1997年畢業(yè)于皖南醫(yī)學(xué)院臨床醫(yī)學(xué)系,獲臨床醫(yī)學(xué)學(xué)士學(xué)位 2002年獲中山大學(xué)臨床腫瘤學(xué)碩士學(xué)位 2005年獲中山大學(xué)臨床腫瘤學(xué)博士學(xué)位 2005年開(kāi)始在中山大學(xué)腫瘤醫(yī)院參加臨床、科研工作 2009年至今擔(dān)任胸科副教授、副研究員、碩士研究生導(dǎo)師 社會(huì)兼職 專(zhuān)業(yè)醫(yī)學(xué)期刊Annals of Palliative Medicine(Pubmed/Medline收錄)主編 專(zhuān)業(yè)醫(yī)學(xué)期刊Journal of Thoracic Disease(Pubmed/SCI收錄)資深編委 國(guó)家肺癌基因庫(kù)專(zhuān)家組成員 中華腫瘤雜志特邀審稿專(zhuān)家. 國(guó)家自然基金評(píng)審專(zhuān)家 承擔(dān)科研課題情況: ① 國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目,30901728、基于數(shù)據(jù)挖掘技術(shù)實(shí)現(xiàn)早期乳腺癌的個(gè)體化預(yù)后預(yù)測(cè)、2009/01-2012/12、20萬(wàn)元、已結(jié)題、主持。 ?、凇V東省科技計(jì)劃項(xiàng)目,060822、肺癌個(gè)體化預(yù)后預(yù)測(cè)、2011/01-2013/12、3萬(wàn)元、在研、主持。 ③ 中山大學(xué)青年培育項(xiàng)目,303045172004、基于個(gè)體化預(yù)后預(yù)測(cè)模型的ⅠB期非小細(xì)胞肺癌術(shù)后輔助化療的前瞻的多中心隨機(jī)對(duì)照研究、2010/01-2013/12、15萬(wàn)元、在研、主持。 ④ 中山大學(xué)腫瘤防治中心優(yōu)秀青年人才培養(yǎng)計(jì)劃, 52010101022005、基于個(gè)體化預(yù)后預(yù)測(cè)模型的ⅠB期非小細(xì)胞肺癌術(shù)后輔助化療的前瞻的多中心隨機(jī)對(duì)照研究、2010/01-2015/12、25萬(wàn)元、在研、主持。 ⑤ 人事部博士后基金,20060390758、硅納米顆粒介導(dǎo)let-7 miRNA靶向治療肺癌的實(shí)驗(yàn)研究、2006/01-2008/12,3萬(wàn)萬(wàn)元、已結(jié)題、主持。 ?、蕖?guó)家863重大專(zhuān)項(xiàng)分題,2006AA02A401、肺癌的分子分型和個(gè)體化診療、2006/01-2011/12,35萬(wàn)元、已結(jié)題、參加。 ⑦ 國(guó)家863重大專(zhuān)項(xiàng)分題,2006AA02A403、食管癌的分子分型和個(gè)體化診療、2006/01-2011/12,70萬(wàn)元、已結(jié)題、參加。 已發(fā)表的論文: 近年來(lái)在Lancet(IF 40)、JCO(IF 18)、JTD、APM等發(fā)表論文30余篇,第一及通訊作者17余篇。研究方向是腫瘤的分子分型、分子分期、個(gè)體化預(yù)后預(yù)測(cè)及診療。 Sun P, Zhang F, Chen C, An X, Li YH, Wang FH, Zhu ZH (2013) Comparison of the prognostic values of various nutritional parameters in patients with esophageal squamous cell carcinoma from Southern China. J Thorac Dis 5:484-91通訊。 Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM (2012) A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet 379:823-32 Xia Q, Zhu Z, Wang J, Situ D, Zhou N, Jang W (2012) Expression and association of HER2 with prognosis in early-stage (T1-T2N0M0) non-small cell lung cancer. Tumour Biol 33:1719-25通訊 Wang J, Ma Y, Zhu ZH, Situ DR, Hu Y, Rong TH (2012) Expression and prognostic relevance of tumor carcinoembryonic antigen in stage IB non-small cell lung cancer. J Thorac Dis 4:490-6通訊 Liu AN;Zhu ZH;Chang SJ;Hang XS (2012) Twist expression associated with the epithelial-mesenchymal transition in gastric cancer.Mol Cell Biochem 367(1-2):195-203共同第一 Hao C, Wei S, Tong Z, Li S, Shi Y, Wang X, Zhu ZH(2012)The effects of RKIP gene expression on the biological characteristics of human triple-negative breast cancer cells in vitro.Tumour Biol 33(4):1159-67 Wang HY, Sun BY, Zhu ZH, Chang ET, To KF, Hwang JS, Jiang H, Kam MK, Chen G, Cheah SL, Lee M, Liu ZW, Chen J, Zhang JX, Zhang HZ, He JH, Chen FL, Zhu XD, Huang MY, Liao DZ, Fu J, Shao Q, Cai MB, Du ZM, Yan LX, Hu CF, Ng HK, Wee JT, Qian CN, Liu Q, Ernberg I, Ye W, Adami HO, Chan AT, Zeng YX, Shao JY (2011) Eight-signature classifier for prediction of nasopharyngeal [corrected] carcinoma survival. J Clin Oncol 29:4516-25共同第一 Situ D, Wang J, Ma Y, Zhu ZH, Hu Y, Long H, Rong T (2011) Expression and prognostic relevance of MUC1 in stage IB non-small cell lung cancer. Med Oncol 28 Suppl 1:S596-604通訊 Hu Y;Ma Y;Wang J;Zhu ZH(2011)Early enteral infusion of traditional Chinese medicine preparation can effectively promote the recovery of gastrointestinal function after esophageal cancer surgery.J Thorac Dis 3:249-54通訊 Sun BY, Zhu ZH, Li J, Linghu B (2011) Combined feature selection and cancer prognosis using support vector machine regression. IEEE/ACM Trans Comput Biol Bioinform 8:1671-7 Situ D, Long H, Lin P, Zhu ZH, Wang J, Zhang X, Xie Z, Rong T (2010a) Expression and prognostic relevance of CD44v6 in stage I non-small cell lung carcinoma. J Cancer Res Clin Oncol 136:1213-9通訊 Situ DR, Hu Y, Zhu ZH, Wang J, Long H, Rong TH (2010b) Prognostic relevance of beta-catenin expression in T2-3N0M0 esophageal squamous cell carcinoma. World J Gastroenterol 16:5195-202通訊 Dai Y, Long H, Lin P, Fu JH, Zhang LJ, Zhu ZH, Zhang X, Rong TH, Su XD (2010) [Impact of the number of resected and involved lymph nodes on the outcome in patients with stage II non-small cell lung cancer]. Zhonghua Zhong Liu Za Zhi 32:436-40 Hu Y, Zheng B, Fu JH, Rong TH, Yang H, Luo KJ, Li YF, Zhu ZH (2010) [Clinical evaluation of endoscopic ultrasonography and CT in the prediction of the resectability of esophageal carcinoma]. Zhonghua Wei Chang Wai Ke Za Zhi 13:205-9 Zhu ZH, Sun BY, Ma Y, Shao JY, Long H, Zhang X, Fu JH, Zhang LJ, Su XD, Wu QL, Ling P, Chen M, Xie ZM, Hu Y, Rong TH (2009) Three immunomarker support vector machines-based prognostic classifiers for stage IB non-small-cell lung cancer. J Clin Oncol 27:1091-9 Zhang X, Lin P, Zhu ZH, Long H, Wen J, Yang H, Zhang X, Wang DF, Fu JH, Fang Y, Rong TH (2009) Expression profiles of early esophageal squamous cell carcinoma by cDNA microarray. Cancer Genet Cytogenet 194:23-9 Zhang X, Zhu ZH, Lin P, Yang H, Fu JH, Zhang LJ, Long H, Wen J, Huang XP, Fang Y, Rong TH (2008b) [Analyzing the profile of chromosomal imbalances in esophageal atypical hyperplasia and early stage esophageal squamous cell carcinoma by 250K Snp Array]. Zhonghua Yi Xue Za Zhi 88:2636-41 Zhang DK, Su XD, Long H, Lin P, Fu JH, Zhang LJ, Ma GW, Zhu ZH, Dai Y, Rong TH (2008a) [Surgical treatment and prognosis in patients with squamous cell carcinoma of thoracic esophagus]. Zhonghua Wai Ke Za Zhi 46:1333-6 Hu Y, Fu JH, Rong TH, Yang H, Huang WZ, Wang G, Zheng B, Zhu ZH (2008) [Diagnostic value of endoscopic ultrasonography and CT in T, N stage of preoperative esophageal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi 11:150-3 Zhang SY, Wang X, Rong TH, Zheng L, Zeng CG, Xie ZM, Yu H, Zhu ZH (2007) [Evaluation of lymph node metastasis in the contralateral mediastinum or scalene through mediastinoscopy and para-mediastinal small incision in potentially operable non-small cell lung cancer]. Zhonghua Zhong Liu Za Zhi 29:629-31 Zhu ZH, Rong TH, Zeng CG, Wu QL, Ma Y, Huang XP, Li BJ, Zhang PY, Zhao JM, Hu W, Zhang SY, Yu H, Ma GW, Zhang LJ, Wen ZS, Fu JH, Long H (2005a) [Vascular endothelial growth factor expression and microvessel density in stage I-II non-small cell lung cancer and their prognostic significances]. Ai Zheng 24:865-9 Zhu ZH, Li BJ, Zhang SY, Rong TH, Zeng CG, Yu H, Hu Y, Zhang X, Fu JH, Long H, Lin P, Wang SY, Wang X, Yang MT, Huang ZF (2005b) [Predictive value of detection of sentinel lymph nodes on lymphatic metastasis of non-small cell lung cancer]. Ai Zheng 24:341-4 Zhang SY, Wang X, Zhu ZH, Zeng CG, Rong TH, Zheng L, Fu JH, Xie ZM, Zhang X, Yu H (2005) [Clinical value of cervical mediastinoscopy in non-small cell lung cancer of stage I]. Ai Zheng 24:349-52 Li BJ, Zhu ZH, Wang JY, Hou JH, Zhao JM, Zhang PY, Yao GY, Wang X, Long H, Yang MT, Rong TH (2004) [Expression correlation of Ki67 to P53,VEGF,and C-erbB-2 genes in breast cancer and their clinical significances]. Ai Zheng 23:1176-9 Ma GW, Rong TH, Long H, Fu JH, Lin P, Huang ZF, Zeng CG, Zhang X, Li XD, Zhang LJ, Wen ZS, Wang JY, Zhang PY, Hu Y, Zhu ZH (2004) [Shrinkage of resected specimens of esophageal carcinoma]. Ai Zheng 23:193-5 詳細(xì)介紹
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